Simul 6.1

Simul is a series of simulation software for electrophoresis which has been continuously developing.

It simulates the movement of ions in liquid solutions in an electric field. It solves numerically a set of nonlinear partial differential equations and nonlinear algebraic equations describing the continuity of ionic movement and acid-base equilibria.

Simul 6.1 is a continuation of the previous version 5. Its code was rewritten using the Qt toolkit so it has become cross-platform software. The computation engine has been completely redesigned in order to take full advantage of parallelization and multithreading computation. It is 5 – 15 times faster than Simul 5.

Simul 6.1 is described in more details in a paper in ELECTROPHORESIS.

The typical use of Simul 6.1:

• to simulate experimental runs and optimize separation conditions (buffers, injection),
• to inspect or explain unusual phenomena observed in experiments: system peaks (zones), overshoots, peak distortion,
• to inspect stacking and preconcentrating analytes, electromigration dispersion,
• to show beginners how electrophoresis works.

Features of Simul 6.1:

• A mathematical model of electromigration which accounts for any number of multivalent electrolytes or ampholytes, even in the hundreds.
• Simul 6.1 includes a database of electrophoretic mobilities and pKa constants based on Takeshi Hirokawa's tables with the data of many ions.